羟基喜树碱/GA-PEI-PLGA纳米粒的制备及其工艺优化*
梁劲康,吴得天,胡巧红,吴雅琼

Preparation and Optimization of Hydroxycamptothecin Loaded GA-PEI-PLGA Nanoparticles
Jingkang LIANG,Detian WU,Qiaohong HU,Yaqiong WU
单因素实验结果

A.有机溶剂系统考察;B.二氯甲烷/甲醇体积比考察;C.油相/水相体积比考察;D.药物/载体比考察;E.超声时间考察;F.超声功率考察;*1表示该纳米悬液静置数天后有沉淀。
Results of single-factor experiments

A.composition of organic phase;B.the volume ratio of dichloromethane to methanol;C.the volume ratio of organic phase to water;D.the mass ratio of drug to carrier;E.sonication time;F.sonication power;*1precipitate was observed a few days after storage of nanosuspension