熊果酸对人卵巢癌耐药SKOV3/DDP裸鼠移植瘤的抑制作用*

杨茗钫,程晓华,刘丝荪,黄欧平

Inhibitory Effect of Ursolic Acid on Drug-resistant SKOV3/DDP Ovarian Carcinoma Xenografts in Nude Mice

Mingfang YANG,Xiaohua CHENG,Sisun LIU,Ouping HUANG

4组荷瘤裸鼠移植瘤组织Bcl-2 mRNA和Bax mRNA表达 A.空白对照组;B.顺铂组;C.熊果酸小剂量组;D. 熊果酸大剂量组;与空白对照组比较,*1P<0.01;与顺铂组、熊果酸小剂量组比较,均*2P<0.05

The mRNA expression of Bcl-2 and Bax in transplantation tumor of four groups of nude mice A. blank control group; B. cisplatin group; C. low-dose ursolic acid group; D.high-dose ursolic acid group; Compared with blank control group, * 1P< 0.01; compared with cisplatin group and low-dose ursolic acid group, * 2P<0.05