微柱离心-HPLC法测定载左旋多巴聚乙二醇化固体脂质纳米粒的包封率*

魏曼,张宇佳,陈谕园,张楠,郑稳生

Determination of Entrapment Efficiency of Levodopa-loaded PEGylated-Solid Lipid Nanoparticles by Mini-Column Centrifugation- HPLC

Man WEI,Yujia ZHANG,Yuyuan CHEN,Nan ZHANG,Wensheng ZHENG

3种溶液HPLC图 A.空白PEG化固体脂质纳米粒;B.左旋多巴对照品溶液;C.左旋多巴PEG化固体脂质纳米粒;1.左旋多巴

HPLC chromatograms of three kinds of solution A.blank PEG-solid lipid nanoparticle;B.levodopa control;C.levodopa PEG- solid lipid nanoparticle;1.levodopa