叶酸壳寡糖修饰的聚乳酸-羟基乙酸共聚物纳米粒对耐紫杉醇人卵巢癌细胞增殖的影响

邓艾平,王奕,刘珏,胡振夏,符旭东

Effect of Poly (lactic-co-glycolic acid) Nanoparticles Surface Modified with Folic Acid Conjuncted Chitosan Oligosaccharide on Proliferation of SKOV-3/TAX Cells

Aiping DENG,Yi WANG,Jue LIU,Zhenxia HU,Xudong FU

不同浓度紫杉醇对SKOV-3(A)和SKOV-3/TAX (B)增殖抑制作用(xˉ±s,n=6) 与TAXOL 组比较,*1P<0.01,*3P<0.05;与PLGA-NPs组比较,*2P<0.01,*4P<0.05

Inhibitory effect of different concentrations of PTX on the proliferation of SKOV-3 (A)and SKOV-3/TAX (B)(xˉ±s,n=6) Compared with TAXOL group;*1P<0.01,*3P<0.05;Compared with PLGA-NPs group, *2P<0.01,*4P<0.05