星点设计-效应面法优化盐酸丁螺环酮胃漂浮缓释片处方*

李雪怡,段颐珊,王珂玉,林宁

Optimization of Formulation of Buspirone Hydrochloride Gastric-Floating Sustained Release Tablets by Central Composite Design/Response Surface Methodology

Xueyi LI,Yishan DUAN,Keyu WANG,Ning LIN

图3 盐酸丁螺环酮于2,4,8 h累积释放百分率的等高线图

Fig.3 Contour map of 2, 4 and 8 h cumulative release percentage of buspirone hydrochloride