星点设计-效应面法优化盐酸罗沙替丁醋酸酯胃漂浮缓释片制剂处方*

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Formulation Optimization of Roxatidine Acetate Hydrochloride Gastric-floating Sustained Release Tablets by Central Composite Design-Response Surface Methodology

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图2 ROX于 1,4,8 h累积释放百分率等高线图

Fig.2 Contour map of cumulative release percentage of ROX at 1,4 or 8 h