萘普生片溶出曲线相似性评价及体内外相关性研究 |
唐婉,尹菁,张圆,石蓓佳,李攀,陆益红,樊夏雷 |
Evaluation the Dissolution Curve Similarity of Naproxen Tablets and Study on the in Vitro-in Vivo Correlation Model |
Wan TANG,Jing YIN,Yuan ZHANG,Beijia SHI,Pan LI,Yihong LU,Xialei FAN |
8种仿制制剂与参比制剂在5种溶出介质中的溶出曲线(n=6) A.pH值6.8缓冲液;B.pH值6.0缓冲液;C.pH值5.5缓冲液;D.pH值1.2溶液;E.水 |
Dissolution curves of generic drugs from eight companies and reference listed drug in five media (n=6) A.pH6.8 solution;B.pH6.0 solution;C.pH5.5 solution;D.pH1.2 solution;E.water |