苦杏仁苷对肾纤维化大鼠的保护作用及其机制*

李想,刘庆,高晨,周红兵,常虹,王佳,白万富,石松利

Protective Effect and Mechanism of Amygdalin on Renal Fibrosis in Rats

Xiang LI,Qing LIU,Chen GAO,Hongbing ZHOU,Hong CHANG,Jia WANG,Wanfu BAI,Songli SHI

图1 6组大鼠肾组织HE、Masson染色及病理评分结果(n=10) A.假手术组;B.模型对照组;C.贝那普利组;D.苦杏仁苷小剂量组;E.苦杏仁苷中剂量组;F.苦杏仁苷大剂量组。①与假手术组比较,t=-11.489~-1.702,P<0.01;②与模型对照组比较,t=2.128~11.489,P<0.01。

Fig.1 HE,Masson staining and pathological score of kidney tissues in six groups of rats(n=10) A.sham group;B.model control group;C.benazepril group;D.amygdalin low dose group ;E.amygdalin medium dose group;F.amygdalin high dose group.①Cmopared with sham group,t=-11.489—-1.702,P<0.01;②Cmopared with model control group,t=2.128—11.489,P<0.01.