苦杏仁苷对肾纤维化大鼠的保护作用及其机制<sup>*</sup>

苦杏仁苷对肾纤维化大鼠的保护作用及其机制^*

李想,刘庆,高晨,周红兵,常虹,王佳,白万富,石松利

Protective Effect and Mechanism of Amygdalin on Renal Fibrosis in Rats

Xiang LI,Qing LIU,Chen GAO,Hongbing ZHOU,Hong CHANG,Jia WANG,Wanfu BAI,Songli SHI

图5 4组大鼠肾组织中TGF-β₁、Smad3 和Smad7 mRNA表达量比较(n=10)
A.假手术组;B.模型对照组;C.贝那普利组;D.苦杏仁苷小剂量组。①与假手术组比较,t=-19.853~6.325,P<0.01;②与模型对照组比较,t=-6.325~19.853,P<0.01。

Fig.5 Comparison of TGF-β₁,Smad3 and Smad7 mRNA levels in renal tissues among four groups of rats(n=10)
A.sham group;B.model control group;C.benazepril group;D.amygdalin low dose group.①Compared with sham group,t=-19.853—6.325,P< 0.01;②Compared with model control group,t=-6.325—19.853,P< 0.01.