救必应对小肠黏膜损伤模型大鼠的防治作用及其机制<sup>*</sup>

救必应对小肠黏膜损伤模型大鼠的防治作用及其机制^*

梁欣仪,李茹柳,刘乙婷,陈婉霞,曾信平,胡玲

The Protective Effect and Mechanism of Ilex rotunda Thunb. in Rat Model of Small Intestinal Mucosal Injury

Xinyi LIANG,Ruliu LI,Yiting LIU,Wanxia CHEN,Xinping ZENG,Ling HU

图3 免疫组化法(IHC)和免疫印迹法(WB)检测4组大鼠E-cadherin、α-catenin和β-catenin蛋白水平及其半定量分析结果(×200)
A.正常对照组;B.模型对照组;C.救必应小剂量组;D.救必应大剂量组。①与正常对照组比较,χ²=-2.806~-2.749(IHC),P<0.05;②与模型对照组比较, χ²=-3.318~-2.693(IHC),P<0.05;③与正常对照组比较,t=-1.731~ 1.773(WB),P<0.01;④与模型对照组比较,t=-0.652~ 1.680(WB),P<0.01。

Fig.3 E-cadherin,α-catenin and β-catenin detected by immunohistochemistry(IHC),Western blotting(WB) and their semi-quantitative analysis results in four groups of rats(×200)
A.normal control group;B.model control group;C.Ilex rotunda Thunb.low dose group ;D.Ilex rotunda Thunb.high dose group.①Compared with normal control group,χ²=-2.806—-2.749(IHC),P<0.05; ②Compared with model control group,χ²=-3.318—-2.693(IHC),P<0.05; ③Compared with normal control group,t=-1.731—1.773(WB),P< 0.01;④ Compared with model control group,t=-0.652—1.680(WB),P< 0.01.