归芍方对邻苯二甲酸二丁酯诱导的斑马鱼眼部细胞凋亡的影响*

李梦雨,华永庆,黄天一,郑云枫,严国俊,程建明,袁晓琳

Effect of Guishao Formula on Dibutyl Phthalate Induced Ocular Apoptosis of Zebrafish

Mengyu LI,Yongqing HUA,Tianyi HUANG,Yunfeng ZHENG,Guojun YAN,Jianming CHENG,Xiaolin YUAN

图1 不同制备工艺归芍方对斑马鱼存活率的影响($\bar{x}\pm s$,n=3) ①与48 h对照组比较,t=10.960~42.750,P<0.01;②与104 μg·mL-1ME(24 h)组比较,t=17.330,P<0.01;③与24 h 对照组比较,t=13.860,17.320,P<0.01;④与104 μg·mL-1 MEA(24 h)组比较,t=8.573,P<0.01;⑤与103 μg·mL-1 PS(24 h)组比较,t=8.552,P<0.01;⑥与104 μg·mL-1 PS(24 h)组比较,t=10.960,P<0.01。

Fig.1 Effects of Guishao formula with different preparation processes on the survival rate of zebrafish($\bar{x}\pm s$,n=3) ①Compared with control group at 48 h,t=10.960—42.750,P<0.01;②Compared with 104 μg·mL-1 ME(24 h) group,t=17.330,P<0.01;③Compared with control group at 24 h,t=13.860,17.320,P<0.01;④Compared with 104 μg·mL-1 MEA(24 h) group,t=8.573,P<0.01;⑤Compared with 103 μg·mL-1 PS(24 h) group,t=8.552,P<0.01;⑥Compared with 104 μg·mL-1 PS(24 h) group,t=10.960,P<0.01.