石菖蒲-远志药对不同组分对阿尔茨海默病模型大鼠海马Tau蛋白及其Ser396位点磷酸化的影响*

张智华,王秀莲,吕银娟,柳琳,吴建红

Effect of Different Components of Acorus tatarinowii and Polygala tenuifolia on p-Ser396 and Tau-5 Expression in the Hippocampus of Rats with Alzheimer's Disease

Zhihua ZHANG,Xiulian WANG,Yinjuan LYU,Lin LIU,Jianhong WU

图3 8组大鼠海马CA1区Tau-5表达的病理特征(×400) A正常对照组;B.模型对照组;C1.石菖蒲-远志挥发油小剂量组;C2.石菖蒲-远志挥发油中剂量组;C3.石菖蒲-远志挥发油大剂量组;D1.石菖蒲-远志水提物小剂量组;D2.石菖蒲-远志水提物中剂量组;D3.石菖蒲-远志水提物大剂量组

Fig 3 Pathological characteristic of Tau-5 expression in hippocampus CA1 region of eight groups of rats(×400) A.normal control group;B.model control group;C1.low-dose volatile oil group of Acorus tatarinowii and Polygala tenuifolia;C2.medium-dose volatile oil group of Acorus tatarinowii and Polygala tenuifolia;C3.high-dose volatile oil group of Acorus tatarinowii and Polygala tenuifolia;D1.low-dose aqueous extract group of Acorus tatarinowii and Polygala tenuifolia;D2.medium-dose aqueous extract group of Acorus tatarinowii and Polygala tenuifolia;D3.high-dose aqueous extract group of Acorus tatarinowii and Polygala tenuifolia