川芎与细辛挥发油β-环糊精包合物成分分析及经皮渗透实验

穆启运,阮新民

Transdermal Penetration Test of Four Preparations Containing Volatile oil Extracted From Chuanxiong Rhizoma and Asari Radix et Rhizoma in Vitro and Its β-cyclodextrin Inclution Complex

Qiyun MU,Xinmin RUAN

4种含川芎和细辛挥发油的物质经皮渗透液的GC色谱图 A.β-CD包合物凝胶膏剂;B.β-CD与挥发油混合物凝胶膏剂;C.β-CD包合物涂敷皮肤上;D.挥发油涂敷皮肤上;1.甘油;2.优葛缕酮;3.冰片;4.松油烯-4-醇;5.α-萜品醇;6.3,5-二甲氧基甲苯;7.黄樟醚;8.甲基丁香酚;9.1,2,3-三甲氧基-5-甲基苯;10.肉豆蔻醚;11.十五烷;12.榄香素;13.百秋李醇;14.3-丁烯基苯酞;15.川芎内酯A;16.顺式-藁本内酯;17.邻苯二甲酸二丁酯

GC chromatogram of Percutaneous penetrative fluid of four substances containing volatile oil extracted from Chuanxiong Rhizoma and Asari Radix et Rhizoma A.cataplasma of β-CD inclusion of the volatile oil,B.cataplasma of a mixture of the volatile oil and β-CD,C.β-CD inclusion of the volatile oil,D.the volatile oil;1.glycerol,2.eucarvone,3.endo-borneol,4.terpinen-4-ol,5.α-terpineol,6.3,5-dimethoxyltoluene,7.safrole,8.methyleugenol,9.1,2,3-trimethoxyl-5-methyl-benzene,10.myristicin,11.pentadecane,12.elemicin,13.patchouli alcohol,14.3-butylidene-1(3H)-Isobenzofuranone,15.senkyunolide A,16.cis-ligustilide,17.di-n-butyl phthalate