LC-MS/MS法同时测定人尿液中氢化可的松和6β-羟基氢化可的松的浓度*

谢利军,杨雨晴,沈叶,应玉雯,黄烽如,张烨,刘云,孙鲁宁,王永庆

Simultaneous Determination of Hydrocortisone and 6β-hydroxycortisone Concentrations in Human Urine by LC-MS/MS

Lijun XIE,Yuqing YANG,Ye SHEN,Yuwen YING,Fengru HUANG,Ye ZHANG,Yun LIU,Luning SUN,Yongqing WANG

氢化可的松,6β-氢化可的松及其内标在水基质中和尿液基质中的色谱图 A.空白样本;B.中浓度质控水基质样本;C.空白尿液样本;D.仅含内标的尿液基质样本

Chromatograms of hydrocortisone,6β-hydroxycortisone and their internal standards in water and urine 1.blank sample;B.quality control sample at medium dose;C.blank urine sample;D.Urine sample containing internal standard