黄连素促进2型糖尿病大鼠胰高血糖素样肽分泌的分子机制

夏敬胜,王倩,邹吉利,蔡瑜,李颖

Molecular Mechanism of Berberine on GLP-1 Secretion in Type 2 Diabetic Rats

Jingsheng XIA,Qian WANG,Jili ZOU,Yu CAI,Ying LI

图7 黄连素对糖尿病大鼠GPR43、TGR5、GCG及PC1/3 mRNA的影响 A.正常对照组;B.模型对照组;C.利拉鲁肽组;D.小剂量组;E.大剂量组;①与正常对照组比较,P<0.01;②与模型对照组比较,P<0.01。

Fig.7 Effects of berberine on the mRNA expression of GPR43, TGR5, GCG and PC1/3 in diabetic rats A.normal control group;B.model control group;C.liraglutide group;D.low-dose of berberine group;E.high-dose of berberine group;①compared with normal control group,P<0.01;②compared with model control group,P<0.01.