沙棘熊果酸对酒精性肝病模型大鼠的保护作用*

李可欣,张男男,侯瑞丽,张文龙,高龙,苗晓涵,戈娜

Protective Effect of Ursolic Acid Extracted from Hippophae rhamnoides L. on Alcohol-Induced Liver Disease in Rats

Kexin LI,Nannan ZHANG,Ruili HOU,Wenlong ZHANG,Long GAO,Xiaohan MIAO,Na GE

图3 5组大鼠肝细胞凋亡率比较($\overline{x}$±s,n=10) A.正常对照组;B.模型对照组;C.熊果酸大剂量组;D.熊果酸中剂量组;E.熊果酸小剂量组。 ①与正常对照组比较,t=-69.823~-9.457,P<0.05;②与模型对照组比较,t=3.561~17.611,P<0.05;③与熊果酸小剂量组比较,t=-6.767,P<0.05。

Fig.3 Comparison of hepatocyte apoptosis rate among five groups of rats($\overline{x}$±s,n=10) A.normal control group;B.model control group;C.high-dose ursolic acid group;D.medium-dose ursolic acid group;E.low-dose ursolic acid group.①Compared with normal control group,t=-69.823--9.457,P<0.05;②Compared with model control group,t=3.561-17.611,P<0.05;③Compared with low-dose ursolic acid group,t=-6.767,P<0.05.