微小RNA-199a-5p对非小细胞肺癌紫杉醇耐药性的影响及其机制*

蒙冲,刘礼荣,刘凯

Effect of microRNA-199a-5p on Paclitaxel Resistance in Non-small Cell Lung Cancer and Its Mechanism

Chong MENG,Lirong LIU,Kai LIU

图3 6组A549/PTX细胞中HSP90、HSP60和P-gp蛋白水($\bar{x}±s$,n=3) A.正常对照组;B.miR-NC组;C.miR-199a-5p组;D.si-NC组;E.si-HSF-1组;F.miR-199a-5p+HSF-1组。①与 miR-NC 组比较,P<0.05;②与si-NC组比较,P<0.05;③与 miR-199a-5p组比较,P<0.05。

Fig.3 Protein levels of HSP90,HSP60 and P-gp in A549/PTX cells in six groups($\bar{x}±s$,n=3) A.normal control group;B.miR-NC group;C.miR-199a-5p group;D.si-NC group;E.si-HSF-1 group;F.miR-199a-5p+HSF-1 group.①Compared with miR-NC group,P<0.05 ;②Compared with si-NC group,P<0.05;③Compared with miR-199a-5p group,P<0.05.