Objective To promote its rational application and provide reference for drug administration by comparing the application of proton pump inhibitors before and after intervention. Methods The unreasonable use of proton pump inhibitors in the department of cardiology was intervened through the development of evaluation criteria for rational drug use, training on rational drug use, comments and communication.and administrative intervention.The total medication use of PPI in cardiology department before and after intervention was compared, including sales amount, utilization rate and drug proportion. 150 cases of hospitalized patients using PPI injection before and after the intervention were randomly selected for rationality analysis. Results Before the intervention, the number of patients with PPI was 2171, it was 1780 after intervention, the decrease rate was 18.01%; The sales amount was changed from 0.9139 million to 0.5587 million, the decline rate was 38.87%.After intervention, the utilization rate of PPI decreased significantly, by 23.57% (P=0.000), and the proportion of PPI drugs was significantly lower than before, too, the decline rate was as high as 51.12%(P=0.000).The proportion of patients who did not have indication of PPI injection was significantly reduced from 17.33% to 5.33%(P=0.001).Prevention using PPI medication indications grasp tighter (P<0.05), and the situation of overdose medication was significantly reduced (P=0.000), the situation of improper drug selection and drug interaction disappeared completely, and the rationality of medication was significantly improved. Conclusion The pharmaceutical intervention of clinical pharmacists can effectively promote the rational use of PPI in cardiology department, and the intervention mode can be used for the special management of other drugs.
张新茹,谢莉娜,王冬雪,侯继秋,付秀娟. 床药师干预心内科质子泵抑制药合理应用的工作模式和效果[J]. 医药导报, 2019, 38(6): 792-796.
Xinru ZHANG,Lina XIE,Dongxue WANG,Jiqiu HOU,Xiujuan FU. Work Model and Effect of Clinical Pharmacist Intervention in the Rational Application of Proton Pump Inhibitor in Cardiology. Herald of Medicine, 2019, 38(6): 792-796.
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