随机抽取我院接受LC患者1 200例,统计姓名、年龄、性别、诊断、入出院时间和抗菌药物使用类别、名称、使用方法、剂量、药物使用时间、联合应用等,传统LC及快速康复LC均为600例。纳入标准为单纯性胆结石、慢性胆囊炎、胆囊结石、胆囊息肉、肝内胆管结石患者,美国麻醉医师协会(American Society of Anesthesiologists,ASA) 评分等级为Ⅰ~Ⅲ级,年龄25~72岁,男女比例0.82:1。剔除标准:剔除糖尿病、冠心病、严重心肺功能损伤及手术前感染并发症等。最后纳入接受传统LC患者 558例(A组),接受快速康复干预LC患者554例(B组)。
DE GEORGE MA,RANGELM,NODA RW,et al.Laparo-scopic transumbilical cholecystectomy:surgical technique[J].,2009,13(4):536-541.
ABSTRACT Laparoscopic cholecystectomy is generally performed using 4 ports by transperitoneal access. Recent developments regarding laparoscopic surgery have been directed toward reducing the size or number of ports to achieve the goal of minimally invasive surgery, by minilaparoscopy, natural orifice access, and the transumbilical approach. The aim of this article is to describe our laparoscopic transumbilical cholecystectomy technique using conventional laparoscopic instruments and ports. The Veress needle was placed through the umbilicus, which allowed carbon dioxide inflow. A 5-mm trocar was placed in the periumbilical site for the laparoscope followed by the placement of 2 additional 5-mm periumbilical trocars. The entire procedure was performed using conventional laparoscopic instruments. At the end of the surgery, trocars were removed, and all 3 periumbilical skin incisions were united for specimen retrieval. Five transumbilical cholecystectomies were performed following this technique. The mean BMI was 26.6 kg/m(2). The mean operative time and blood loss were 46.2 minutes and 55 mL, respectively. No intraoperative complications occurred. Analgesia was performed using dipyrone (1g IV q6h) and ketoprofen (100 mg IV q12 h). Time to first oral intake was 8 hours. Mean hospital stay was 19.2 hours. Laparoscopic transumbilical cholecystectomy seems to be feasible even using conventional laparoscopic instruments and can be considered a potential alternative for traditional laparoscopic cholecystectomy.
SHAH JN,MAHARJAN SB,PAUDYALS.Routine use of antibiotic prophylaxis in low-risk laparoscopic cholecys-tectomy is unnecessary:a randomized clinical trial[J].,2012,35(4):136-139.
Routine preoperative antibiotic prophylaxis is not necessary in low-risk symptomatic gallstone patients undergoing laparoscopic cholecystectomy.
PATEL GN,RAMMOS CK,PATEL JV,et al.Further reduction of hospital stay for laparoscopic colon resection by modifications of the fast-track care plan[J].,2010,199(3):391-395.
Abstract BACKGROUND: Fast-track surgery has been described as a plan to facilitate early recovery. We present one surgeon's modifications to fast-track surgery for laparoscopic colectomy patients. METHODS: We performed a retrospective review of 48 consecutive patients undergoing elective laparoscopic colectomy treated by a modified fast-track plan between 2004 and 2008. Elements included preoperative education, pre-anesthesia dexamethasone, immediate postoperative general diet, no urinary catheter, no epidural anesthesia, and no flatus or bowel movement as a discharge requirement. Data collected included the following: age, sex, body mass index, resection indications, surgical time, blood loss, pain score, time to ambulation, time to bowel function, length of stay, complications, and mortality. RESULTS: The mean length of stay was 37 hours (1.5 d), with 29 of 48 patients discharged without passage of flatus or stool. Only 1 patient required readmission. CONCLUSIONS: Our modified fast-track plan achieved significant improvement in length of stay for laparoscopic colectomy compared with previous results. Copyright (c) 2010 Elsevier Inc. All rights reserved.
NANAVATI AJ,NAGRALS,PRABHAKARS.Fast-track surgery in India[J].,2014,27(2):79-83.
Abstract Fast-track surgery or 'enhanced recovery after surgery' or 'multimodal rehabilitation after surgery' is a form of protocolbased perioperative care programme. It is an amalgamation of evidence-based practices that have been proven to improve patient outcome independently and exert a synergistic effect when applied together. The philosophy is to treat the patient's pathology with minimal disturbance to the physiology. Several surgical subspecialties have now adopted such protocols with good results. The role of fast-track surgery in colorectal procedures has been well demonstrated. Its application to other major abdominal surgical procedures is not as well defined but there are encouraging results in the few studies conducted. There has been resistance to several aspects of this programme among gastrointestinal and general surgeons. There is little data from India in the available literature on the application of fast-tracking in gastrointestinal surgery. In a country such as India the existing healthcare structure stands to gain the most by widespread adoption of fast-track methods. Early discharge, early ambulation, earlier return to work and increased hospital efficiency are some of the benefits. The cost gains derived from this programme stand to benefit the patient, doctor and government as well. The practice and implementation of fast-track surgery involves a multidisciplinary team approach. It requires policy formation at an institutional level and interdepartmental coordination. More research is required in areas like implementation of such protocols across India to derive the maximum benefit from them. Copyright 2014, NMJI.
AKOH JA,WATSON WA,BOURNE TP.Day case laparoscopic cholecystectomy:reducing the admission rate[J].,2011,9(1):63-67.
Appropriate patient selection, sensible scheduling of operations and avoiding the use of drains will decrease unplanned admissions following DCLC. Although the time taken to perform procedures was higher for surgical trainees than consultants, this had no adverse outcome on patient outcome.
ANSALONIL,PISANOM,COCCOLINIF,et al.2016 WSES guidelines on acute calculous cholecystitis[J].,2016,11:25.
Acute calculus cholecystitis is a very common disease with several area of uncertainty. The World Society of Emergency Surgery developed extensive guidelines in order to cover grey areas. The diagnostic criteria, the antimicrobial therapy, the evaluation of associated common bile duct stones, the identification of “high risk” patients, the surgical timing, the type of surgery, and the alternatives to surgery are discussed. Moreover the algorithm is proposed: as soon as diagnosis is made and after the evaluation of choledocholitiasis risk, laparoscopic cholecystectomy should be offered to all patients exception of those with high risk of morbidity or mortality. These Guidelines must be considered as an adjunctive tool for decision but they are not substitute of the clinical judgement for the individual patient.
SARTELLIM,WEBER DG,RUPPEE,et al.Antimicrobia-ls:a global alliance for optimizing their rational use in intra-abdominal infections(AGORA)[J].,2016,11:33.
Abstract [This corrects the article DOI: 10.1186/s13017-016-0089-y.].
YAN RC,SHEN SQ,CHEN ZB,et al.The role of prophy-lactic antibiotics in laparoscopic cholecystectomy in preventing postoperative infection:a meta-analysis[J].,2011,21(4):301-306.
Although laparoscopic cholecystectomy (LC) is a common and widely applied technique, the use of antibiotics during the perioperative period in infection prevention remains controversial. In our study, a meta-analysis was performed to assess the impact of antibiotic prophylaxis on the postoperative infection rate in LC.A literature search was conducted on studies published between January 1966 and March 2010 that involved LC and prophylactic administration of antibiotics. Only randomized trials that compared perioperative antibiotic prophylaxis with placebo or no treatment in low-risk patients undergoing LC were selected. Eighteen studies qualified according to the inclusion criteria, but only 12 were of adequate quality according to the Jadad scale to be included for the meta-analysis. Data were analyzed via the Peto odds ratio (OR) method and run using RevMan 4.2 software. The precision of the estimation of OR by individual studies was used to calculate their contribution (or weighting) to the pooled OR.The results of the 12 studies did not have significant heterogeneity, and thus, the fixed effect model was used for data analysis. Compared with placebo or no treatment, there was no significant risk reduction in the antibiotic prophylaxis group with regard to overall infections (OR=1.11; 95% confidence interval [CI], 0.68-1.82; P=.67), wound infections (OR=1.07; 95% CI, 0.59-1.94; P=.99), major infections (OR=2.88; 95% CI, 0.3-28.09; P=.36), distant infections (OR=1.01; 95% CI, 0.43-2.36; P=.99), or positive bile cultures (OR=0.76; 95% CI, 0.54-1.08; P=.12). However, prophylactic antibiotics did shorten length of hospital stay (weighted mean difference=-0.16; 95% CI, -0.22 to -0.09; P<.01).Prophylactic antibiotics are not necessary for elective LC in low-risk patients.